Diflucan and Early Pregnancy: Risks and What to Do

Question
Hi,

I had taken two tablets of diflucan150mg for east infection and today I found out I'm 5 weeks pregnant.I had the first tablet on the third week and second on the fourth week of my pregnancy.I'm worried about the ill effects of this medication on my baby and my next appointment with doc is going to be only after 3 weeks.Is there any side effects of this medicine that I should be conerned about and any tests I should be tested for?Thank you for your time .

Answer
Diflucan (fluconazole) is a synthetic triaxzole antifungal agent. In studies with pregnant rabbits, abortions were noted at a dose twenty to sixty times the recommended human dose but no fetal anomalies. However, although the data are very limited, the use of Diflucan during the first trmester appears to be teratogenic with continuous daily doses of 400 mg per day or more. The published experience with the use of smaller doses, such as those prescribed for vaginal fungal infections, suggests that the risk for adverse outcomes is low, if it exists at all. Since you used Diflucan twice and it was a small dose of only 150mg each week, I think you have nothing to worry about.