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Medication Interactions: Safety of Gabapentin, Baclofen, Ibuprofen, Sertraline & Pantoprazole


Question
Pain management initially prescribed gabapentin (2400mg/day) baclofen (10mg/3 per day) and vicodin (5mg/500mg; one or two every six hours) for facial pain.  Now they want to slowly get me off of vicodin and has prescribed me ibuprofen (800mg/1 every 8 hrs) sertraline (50mg/1 per day) and pantoprazole (40mg/1 per day); and I continue taking the baclofen and gabapentin at same dosage.
I was wondering are these medications safe to take together; especially regarding the vicodin and ibuprofen? Thank you for your time.

Answer
Dear Lisa,

I am so sorry you have been so uncomfortable.  You didn't say what the problem is, but I am guessing it is Bell's palsy?

I cannot find any documentation telling me that the medications cannot be taken together as prescribed.  Neurontin, Zoloft and Vicodin certainly can be sedating, so I would exercise caution when taking these medications.  

Vicodin and ibuprofen certainly can be taken together.  In fact, there is a medication called Vicoprofen, that is a combination of the two.   I am guessing they started you on te pantoprazole to protect your stomach from the ibuprofen and vicodin.  

I hope this was of help to you.  If I did not answer this question appropriately, please don't hesitate to let me know.

My best wishes to you,

Andrea