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Foot Puncture Wound: Seeking Advice After Doctor Visit


Question
Hi,
I stepped on a long screw today that went in about 1/8 to 1/4 inch into my heel. I had on socks, no shoes, and was inside the house (we are remodeling). It bled alot and I poured hydrogen peroxide on it, added triple antibiotic ointment and a bandage. I called my doctor who saw me immediately for a tetanus booster and soaked my foot in what I think was water and hydrogen peroxide. Then he gave me a 10 day supply of Keflex.
I am asking you because I need to do something about this medication ASAP and it is Friday and he is not available until Monday.
I realized tonight that Keflex gives me painful lasting diarrhea after a few days and I really do not want to take it. I do not know why he gave this to me as there was no inflammation or signs of infection (though I realize it may be early for that to appear). I do not want to take this medication at all, but I do recall from the days I worked for a doctor that Keflex can be taken in 1 or 2 large doses before an infection sets in, prophylactically. I have searched the Internet and, though I have found references to this, I cannot find what the exact dosage is. He gave me 500mg capsules. Can you tell me what standard practice is for giving one or two massive doses for prevention in puncture wounds? I want to say it was 2000 mg but not sure that is correct.
Thank you for your timely response, I know the sooner I take these the better my chances are.

Answer
there is no hard science behind this and no direct evidence that Keflex really helps prevent the infection.....  I tend to treat with normal doses for a short course like 5 days, and have elected to simply watch without antibiotics until I saw definite evidence of an infection, like drainage, redness, etc.  So it becomes a judgement call....   good luck with it.