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Understanding IHC Test Results After Breast Cancer Surgery


Question
Hi,

My mother recently underwent modified radical mastectomy of right breast after being diagonosed with Infiltrating Duct Carcinoma, Grade II (NBR Score 7)  This was followed by a IHC test whose results showed as mentioned :

1) Estrogen Receptor (ER) Score 2/8 Negative
2) Progestrone Receptor (PR) Score 2/8 Negative
3) Her-2neu )c-erb B2) " Score-0 Result Negative.

What does this mean ?

Thanks in advance for your kind response.

Regards
Somnath  

Answer
She has been treated for a breast cancer of medium malignancy originating in the inner lining of a milk duct. The tumour does not have any hormone receptors so any hormonal treatment of this is meaningless. Also there is no sign of any Her-2 which is good for such cancers are more aggressive. But of course I can not give you any guarantees!

I have some computer problems so unfortunately my reply is delayed.

You can also reach me on: http://www.lifestylerescue.com/expert/health-fitness-advice/dr-claes-gustaf/128