If you found yourself in the middle of the never-ending retinol vs. retinoid debate, you are not alone. People often confuse the two and use them interchangeably. However, both are vitamin A derivatives and are the same, except for a few differences. This article attempts to settle the debate and clear your confusion. Keep reading to learn the differences between retinol and retinoid and understand which one is good for your skin.
Retinoid is a vitamin A derivative and umbrella term for all vitamin A derivatives, including retinoic acid, retinol, retinol propionate (pro-retinol), and retinol palmitate.
Dermatologists prescribe retinoids for acne and improve skin health due to their stunning results on most skin types. It is often confused with retinol.
Allison Barbera, a blogger, takes us on her journey with retinoid. She shares her cautious approach, including a patch test and delayed initiation to avoid sun sensitivity. And she also adds, “There are great products in the skincare world that can moisturize, exfoliate, brighten, etc. But I think for serious anti-aging results, prescription retinoids are the way to go (i).”
Retinol is a type of retinoid and much milder than retinoid. You do not need a prescription to get retinol for acne, and it is a common ingredient in OTC skin care products. However, retinol differs from retinoids at a molecular level, and although both have similar benefits, the effects of retinol are much milder than retinoids.
Trivia
Retinol is known for its instability, especially when exposed to air and light. Skin care products containing retinol often come in opaque or airtight packaging to preserve its potency.
Let’s understand it in detail in the next section.
The similarity between the two ingredients is – they provide the same benefits. However, the rate at which you may see the improvements might differ due to the difference in strengths.
Vitamin A is fat-soluble. When you apply retinoids or retinol to your skin, it penetrates the stratum corneum (the topmost layer of the epidermis) and the dermis (the second layer). It binds with the receptors in the keratinocytes (epidermal cells) and stimulates them and the fibroblasts (cells that produce collagen). In other words, retinoids and retinol stimulate the skin cells to (1):
OTC retinol products are often combined with other ingredients. These products are gentler than prescription retinoids; however, you have to be patient and use them continuously to see visible results.
The side effects of retinol and retinoids are also similar, except for the intensity. If you start using any of them without knowing the right concentration and the proper way, you may experience side effects. Let’s take a look.
If your skin is not used to retinoids and retinol and if you use them every day, you may experience:
These symptoms may occur due to the increase in skin cell turnover rate. The best way to avoid this adverse effect is to start with the lowest concentration of retinol. If you are using prescription retinoids, the doctor will gradually increase the strength, depending on the skin tolerance levels and condition.
Some other side effects of retinoids include:
However, retinol and retinoids are not safe to use during pregnancy. Avoid them if you have conceived or are breastfeeding.
If both retinol and retinoids have similar benefits, why not use any of them interchangeably? How do the two ingredients differ? Let’s find out.
Retinol and retinoids differ in two aspects:
Typically, most prescription retinoids have a higher potency than retinol. They are available in topical and oral form, but only on prescription. Tretinoin for acne is often prescribed to combat those pesky zits. Tazarotene is another option.
Retinol is the mildest of all retinoids, and that is why it is often suitable for sensitive and dry skin. However, the way your skin will react to retinol depends on how it can handle the ingredient. Usually, OTC skin care products contain retinol in concentrations between 0.00015% and 0.3% (1). So, you can start with the lowest concentration.
Retinol converts to retinoic acid through a two-step oxidation process. Due to this, retinol takes longer to show visible results as opposed to other types of retinoids, which are potent and show results faster. Retinol products may take at least three months to show results, while most retinoids may give you visible results within six weeks.
There are certain things you need to keep in mind when using retinol or retinoids.
Remember that retinoids and retinol can make your skin photosensitive. So, you cannot skip sunscreen lotion if you are using retinoids during the daytime. Here are a few more guidelines:
Did You Know?
David Adriaan van Dorp and Jozef Ferdinand Arens were the first chemists who discovered retinoic acid in the 1940s.
Depending on your skin concern and time frame of results, you can choose between retinol and retinoids.
Go for retinol if:
Use potent retinoids (with doctor’s prescription) if:
Consult a dermatologist and get your skin analyzed to understand the proper strength of retinoids that might work for you. Chronic acne often requires oral antibiotics or retinoids. The doctor can suggest proper treatment measures depending on your skin condition. Retinoids are beneficial for the skin. However, they are not a one-size-fits-all – not everyone can use retinol and other retinoids.
Avoid topical retinoids and retinol if:
Avoid oral retinoids if you are pregnant, as they may cause congenital disabilities in the baby (2).
Retinol or any other retinoids shouldn’t be used with several other ingredients as that may irritate the skin.
Retinol and retinoids are potent ingredients that accelerate cell regeneration. They shouldn’t be mixed with any other potent ingredients as that can dry out the skin and cause further irritation. Do not mix retinoids with:
Never use retinol and retinoids before waxing or shaving the skin and before laser treatments. The skin remains fragile after such treatments and procedures, and retinoids can further irritate it. Also, never mix multiple retinol products. This can cause inflammation.
Before layering your retinol with other products, make sure you read the ingredient list to see and avoid the above ingredients.
Understanding the role of vitamin A for skin is crucial before you go to comparing retinoids and retinol. Though retinoids and retinol are both derivatives of vitamin A, they differ in two aspects. Retinol is a milder form of retinoid and takes more time to show its results than the stronger retinoid. Both retinoids and retinol boost collagen production, reduce wrinkles and improve skin texture. However, exercise caution while using both products as it may result in redness and irritation. Pregnant women and nursing mothers should avoid using retinoids and retinol as they may cause congenital difficulties in babies. Consult a doctor to put the confusing debate of retinol vs. retinoids to rest.
At what age should you start using retinol?
You can start using retinol in your mid-twenties or early thirties. This is the point at which elastin production begins to slow down. However, depending on your skin type, a dermatologist may advise you to start using retinol at different ages.
Can I use retinol product and retinoid product together?
A cosmetic retinol product can be used along with a retinoid product prescribed by a physician. You get to choose the order in which you use them. It’s important to remember that more is not always better. Stop using multiple retinol products or lower the frequency of use if your skin gets irritated.
Know the difference between retinoids and retinol in the video below. Gain insights into these ingredients from benefits to side effects, and choose the right skin care ingredient accordingly.
Was this article helpful?
Reviewer Author Editor Fact Checker

Dr. Manasi Shirolikar is a consultant dermatologist with over 4 years of experience, practicing in India. Her love for skin care and tryst with childhood and teen acne drive her to help her patients achieve healthier skin in a relatable and easier manner.
Read full bio of Dr. Manasi Shirolikar

Ramona is an editor at StyleCraze with 11 years of experience in writing and editing. She has authored over 200 articles on skin and hair care. She graduated from the University of Calcutta, West Bengal, and did her post-graduation from the University of Kalyani, West Bengal.
Read full bio of Ramona Sinha

Eshna is an associate editor and a certified skin care coach. She has over three years of experience, a triple main bachelor’s degree in psychology, English, and journalism from Mount Carmel College, Bengaluru, and a master’s degree in psychology from Sampurna Montfort College, Bengaluru.
Read full bio of Eshna Das

Monomita has a graduate degree in mass communication and video production from St. Anthony's College, Shillong, and a master’s degree in journalism and mass communication from the Royal Global University, Guwahati. She is also a certified skincare coach with a keen interest in skin, hair, tattoos, nail art, and lifestyle trends.
Read full bio of Monomita Chakraborty