Premarin: Understanding Estrone Sulfate and Hormone Replacement Therapy

Premarin is a type of treatment called Hormone Replacement Therapy (HRT) and contains the hormone oestrogen in the form known as conjugated oestrogens. This drug helps to relieve the discomfort many women feel during and after menopause, including symptoms such as "hot flushes", sweating and vaginal dryness. It helps to prevent thinning of the bones (osteoporosis), which can cause fractures. It is also used to treat women where either the ovary does not function properly or has been removed. If your doctor thinks you will need to take oestrogens for a long time, including for the prevention of osteoporosis, he or she will have considered the benefits and risks of other treatments before prescribing Premarin for you. Precautions : • Do not take this product if you have or have had any of the following medical conditions: • Breast cancer • Endometrial or cervical cancer • Abnormal genital bleeding, which your doctor has not investigated. • A problem with blood clots forming in your blood vessels, such as painful inflammation of the veins (thrombophlebitis) or the blockage of a blood vessel in the legs (deep vein thrombosis or DVT), or lungs (pulmonary embolism) • Heart disease or stroke • Very high blood pressure that is not properly controlled • Problems with your breasts that your doctor has not investigated • Liver disease • Blood clotting problems.