Nail polish, in general, does not contain enzymes. Enzymes are biological catalysts that speed up chemical reactions, and they are not necessary or typically found in nail polish formulations. Nail polish is primarily a mixture of polymers, solvents, pigments, and other additives.
However, there may be exceptions to this rule if the nail polish is specifically designed for therapeutic purposes, in which case it could contain an enzyme to achieve a specific therapeutic effect.